OpenBIO® is designed to serve as the central platform for laboratory, process development, and manufacturing in the biotech and biopharmaceutical industries. Emphasizing recipe-based operations and seamless connectivity, it provides the most flexible platform to facilitate scale-up, scale-down, and technology transfer.
Open, Smart, Scalable Bioprocessing
Why Catalyx is the Partner You Need for Bioreactor Control
Unmatched Bioprocessing Expertise
Rely on a world-class team with decades of experience in biomanufacturing, process automation, and mission-critical operations.
Open Innovation, On Your Terms
Enjoy true freedom to innovate—Catalyx’s bioreactor controllers are never locked down, giving you confidence in your technology roadmap.
Proven Success, Trusted Support
From deployment to optimization, our experts guide you every step of the way, ensuring your projects stay on track and on time.
Open Architecture
OpenBIO delivers an open architecture that accepts any sensor, vessel, pump, probe, or analytical platform, creating a unified and flexible control environment. Teams can reuse existing equipment or build new configurations while maintaining consistent recipe based operation. The system adapts to glass, single use, and stainless steel vessels and supports advanced control strategies for DO, pH, temperature, and feeding. It connects seamlessly with PAT tools and enterprise data systems and provides centralized oversight of multiple vessels and process areas from a single interface, with shared recipes and formulas across the suite.
Hardware Architecture Built for Every Process
OpenBIO offers a configurable hardware foundation that adapts to early research, pilot work, and commercial scale needs. Available features include mass flow controllers with complete gas mixing assemblies that enable precise premixing of air, oxygen, nitrogen, and carbon dioxide, integrated agitation for autoclavable and single use vessels, high resolution pH and dissolved oxygen transmitters, multiple front mounted peristaltic pumps, precision heating and temperature management, and multiple high accuracy scales. This flexibility ensures that laboratories can adopt new technologies without replacing validated equipment.
The Next Generation of Process Automation & Controls
| Other Controllers | |||
|---|---|---|---|
| Open – Any counts of devices | Both OpenBIO and other bioreactor controllers support any number of devices, but traditional models require complex integration. | ||
| Open – Vessel Agnostic | Traditional systems generally lack vessel agnosticism and require manual configuration. The OpenBIO bioreactor controller is fully vessel agnostic. | ||
| Open – Multiple DCS | While traditional controllers may be limited to specific DCS systemS, OpenBIO bioreactor control system inherently support multiple DCS platforms. | ||
| Open - Any vendor of devices | Traditional bioreactor controllers often struggle with consistent vendor support, while OpenBIO maintains uniform compatibility across devices from different manufacturers. | ||
| Average Lead Time | Traditional bioreactor control systems often have long lead times, while the OpenBIO bioreactor controller can be fully integrated within 12–16 weeks. | ||
| Tablet & Browser HMIs | Fixed and proprietary interfaces dominate traditional systems, limiting mobility, while OpenBIO supports tablet and browser-based HMIs for on-the-go monitoring. | ||
| PAT Ready | Traditional bioreactor controllers often lack direct PAT integration, demanding custom solutions, while OpenBIO comes fully prepared. |
OpenBIO®: Designed for the Future of Biomanufacturing
Advanced PAT Integration
Seamless connectivity to PAT ecosystems such as SynTQ and SIPAT provides deeper process insight, while an open scripting environment supports custom algorithms for advanced optimization and rapid method development.
Fed Batch and Perfusion
Automated management of media additions, feeding events, harvest timing, and perfusion module coordination creates a flexible control environment.
Scale Up and Compliance
A consistent control model across benchtop, pilot, and production environments. Comprehensive validation services, installation and commissioning support, testing, IOQ, and optional twenty one CFR eleven packages.
Proven Business Impact
75%
14
400000
Adaptive control cuts downtime and smooths bioreactor transitions
Up and running quickly with no disruption
Full oversight from any location
Award-Winning Innovation
OpenBIO® received the 2018 Innovator Award from Pharmaceutical Manufacturing Magazine for advancing open-architecture bioprocess control and driving smarter, more flexible manufacturing.
CUSTOMER STORY
PROCESS & PACKAGING AUTOMATION:
Pharmaceutical Company Achieves Real-Time Bioreactor Control, Reducing Batch Time by 57%
A pharmaceutical company integrated Endress+Hauser Raman analyzers with the Catalyx OpenBIO® Bioreactor Controller to enhance process efficiency. This real-time solution eliminated manual sampling, reduced contamination risks, and cut batch time from seven to three days, achieving an ROI of $300,000 per unit annually.
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